new pathways to therapeutics

MEDROS

 

Src-driven model of cell overgrowth and metastasis:




Ret-based model of oncogenesis




Multigenic cancer models:




Diabetes


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We have utilized this Src-based model of overgrowth and metastasis to screen a 6,500 compound... read more...Technology-_Csk_Src_model.html
A model of Ret-based diseases provides a strong validation of our approach... read more...Technology-_Ret.html
Drosophila allows us to embrace the complexity of multigenic tumors... read more...Technology-_Multigenic_cancer.html

Modeling cancer metastasis and diabetes: a more detailed view


The Medros approach in cancer identifies drugs with novel mechanisms that prevent metastasis, as well as inhibit tumor growth. The complex, sophisticated models created by Medros are relevant to human breast and lung cancer. For diabetes, we focus on diet-induced obesity and the resultant damage.

Wild-type Drosophila are fed a high carbohydrate diet to model the full complexities of diet-induced obesity and diabetes... read more...Technology-_Diabetes.html
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